Vesi-SEC
Isolate and purify samples before analytics and functional assays.
Essential Solutions for Extracellular Vesicle and Nanoparticle Research
From isolation to analysis, our products are engineered to meet the unique challenges of nanoscale research, ensuring greater speed, reproducibility, and confidence in every experiment.
From isolation to analysis, our products are engineered to meet the unique challenges of nanoscale research, ensuring greater speed, reproducibility, and confidence in every experiment.
Vesi-Dye LMB
Specific staining of lipid bilayers in exosomes, liposomes and viruses.
Vesi-Ref
Extracellular vesicle and liposome reference materials for flow cytometry and other analytical methods
Vesi-Safe
Stabilisation & storage buffer for extracellular vesicles
Pre- and post-analysis reagents for bio-nanoparticle analysis
Improve and accelerate your extracellular vesicle research workflow from Isolation to functional assays.
Thanks to Vesi-SEC columns, it is now possible to isolate EVs by size exclusion chromatography with just one minute spin at low centrifugation speed (1,000g).
Once EVs have been isolated, they can be stabilised for weeks to years using Vesi-Safe, a PBS-based buffer contains ingredients that prevent vesicle loss to adhesion to plastics. Finally, in order to make EVs detectable by fluorescence-capable technologies, these can be specifically and permanently stained with Vesi-LMB probes, which specifically intercalate in the membrane lipid bilayer. Excess dye is swiftly removed by Vesi-SEC Micro spin columns. Positive controls and calibration of these experiments can be performed using the Vesi-Ref family of reference materials.
Cleaning lipid nanoparticles and liposomes post-formulation/-surface chemistry
Removing unbound material from drug-loaded nanocarrier is essential to assess their true therapeutic or immunologic effect.
Size-exclusion chromatography is vastly superior to standard filtration, but in its traditional form, it is labour-intensive, time consuming and dilutive, making it difficult to implement in formulation development operations. Vesi-SEC spin columns are only fast, but also highly scalable, with their format compatible with standards centrifuges, allowing capacities of over 100 columns simultaneously. Unbound material is immobilised on the column’s stationary phase and the purified LNP or liposome sample recovered in just 1 minute.
The nanoscale opens a new frontier in life sciences, but only dedicated protocols can deliver its true potential.
The nanoscale sits at the critical intersection between cells and proteins, a space where biology reveals new layers of complexity and opportunity.
Exploring this frontier requires more than just advanced analytical devices, it also demands the right reagents and carefully designed protocols to capture the correct phenomena and avoid misleading artifacts. Only by combining precision instrumentation with purpose-built staining, stabilisation, and reference tools can researchers draw reliable conclusions that expand scientific understanding. Vesiculab understands these requirements, and develops solutions that help deepening our knowledge of fundamental biological processes and accelerates the translation of discoveries into diagnostics and therapies.
Vesiculab enhances the potential of the following analytical techniques:
NTA
Nanoparticle Analysis
DLS
Dynamic Light Scattering
nFCM
Nano-Flow Cytometry
ILM
Interferometric Light Microscopy
TEM
Transmission Electron Microscopy
RPS
Resistive Pulse Sensing
SP-IRIS
Single Particle Interferometric Reflective Image Sensing
dSTORM
Direct Stochastic Optical Reconstruction Microscopy
Latest News from Vesiculab
Stain, Purify, Analyse – Building Reliable Fluorescent EV Workflows
Stain, Purify, Analyse – Building Reliable Fluorescent EV Workflows
Introducing Vesi-Omics: Fast, efficient and scalable isolation of extracellular vesicles from plasma
Introducing Vesi-Omics: Fast, efficient and scalable isolation of extracellular vesicles from plasma
Watch Rachel Butler’s webinar on our YouTube channel
Watch Rachel Butler’s webinar on our YouTube channel
Vesi-Dye LMB + Vesi-SEC Micro workflow for cell-uptake assay
Vesi-Dye LMB + Vesi-SEC Micro workflow for cell-uptake assay
Vesi-SEC Micro Featured in Two Key EV Research Studies
Vesi-SEC Micro Featured in Two Key EV Research Studies
FSEV 2025: Vesiculab CEO to Present EV Research Solutions
FSEV 2025: Vesiculab CEO to Present EV Research Solutions
Vesiculab Sponsors the Virtual European Flow Core Meeting 2025
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